Advances in Diagnosis and Treatment of Neuromuscular & Neurodegenerative Disorders: What’s Changed in 2016? – Susan Fralick-Ball

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New Findings, Updates, and Treatments:

• Innovative Treatment Regiments for PTs, OTs and SLPs
• Genomic Markers for Diagnosis and Treatment
• Medications vs. Hands-On Treatment
• Symptom Management and Long-Term Care

Multiple Sclerosis, Parkinson’s Disease & Chameleons, Myasthenia Gravis vs. Lambert-Eaton Myasthenic Syndrome, Muscular Dystrophy, Guillain-Barré Syndrome, Chronic Inflammatory Demyelinating Polyneuropathy/Polyradiculopathy, Amyotrophic Lateral Sclerosis/ Motor Neuron Disease

These disorders remain the nation’s leading causes of disability. They are devastating and costly. Due to the aging population, the incidence of these disorders is increasing rapidly. There is a need to provide early diagnosis and apply effective therapies for these disorders. Join expert, Susan Fralick-Ball, PsyD, MSN, CLNC, CH, to learn new strategies for pathophysiologic changes, clinical manifestations, and diagnostic studies for each of these disorders. Gain information on the latest innovative drugs that are geared to slow or stop the disorder progression. Through an engaging presentation style and enlightening case studies, Dr. Fralick-Ball will enhance your knowledge regarding current practice issues. The evidence-based content will improve outcomes for your patients with neuromuscular and neurodegenerative disorders.

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1. Specify the preeminent medication management for multiple sclerosis and its complications.
2. Breakdown the most recent diagnostic indicators for multiple sclerosis.
3. Present your knowledge of Parkinson’s disease and its variants.
4. Communicate common side effects to Parkinson’s medications.
5. Analyze the pros and cons of medications vs. hands-on treatment for these diseases.
6. Investigate the differences in myasthenic and cholinergic crisis.
7. Explore the long-term care for muscular dystrophies.
8. Formulate the syndrome variants for the patient with Guillain-Barré and CIDP.
9. Investigate the symptom management for the patient with Amyotrophic Lateral Sclerosis.
10. Explore newly found genomic markers for diagnosis and treatment of these disorders.

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Multiple Sclerosis

• 4 classifications
• Risk factors: Low Vitamin D, abnormal lipid metabolism
• Making the diagnosis 1-2-3
  • Neuromyelitis Optica, nystagmus
  • Genomic markers
• MRI plain and 3-D
• Treating multiple complications
• Get Dancing and Get on a Bike exercises for MS
• Medication updates 2016
• Case Study

Parkinson’s Disease

• Degeneration, Decline, and Autonomic Disease
  • A Prion Disease?
• T-R-A-P symptoms
• Non-motor complications
• Biomarkers, LRRK variants
• Medical treatment
  • Medications
  • Neuroprotection
• Surgical treatment
  • Palidotomy, Thalamotomy, DBS, Stem cell transplantation
• New PT/OT/SP guidelines for early engagement
  • Bikes, boxing, Big & Loud programs, forced exercise
  • Electrical stimulation
• PD chameleons
  • Essential Tremor
  • Progressive supranuclear palsy
  • Corticobasilar degeneration
• Case Study

Myasthenia Gravis

• Neuromuscular Junction Disorder
  • Autoimmune
  • T-cell interference at NMJ
• Edrophonium (Enlon™) Test for Diagnosis
  • MG vs. Lambert-Eaton
• Short-acting anticholinesterase inhibitors
• Thymectomy
• Crisis: Myasthenic vs. Cholinergic
• Emergent Treatment: Steroids, IVIG, Plasma
• Exchange
• Case Study

Muscular Dystrophy

• Symptoms & causes
• Complications over time
• Treatment: Medical and surgical
• Case Study

Guillain-Barré Syndrome

• Syndrome of peripheral demyelination
  • Ascending
  • Pure motor
  • Descending
  • Miller-Fisher
• Early diagnosis, earlier recovery
• Causes: Viral, bacterial, surgical, vaccines, hyponatremia
• Medical treatment: The Big 3 (steroids, IVIG, Plasmapheresis)
• PT/OT/ST/Psych guidelines
• Case Study

Chronic Inflammatory Demyelinating Polyneuropathy/radiculopathy

• The elusive diagnosis dilemma
  • Symptoms, testing
• Medical treatment for the short- and long-term
  • Living with neuropathic pain
  • Medication, spinal/brain stimulation
• Best PT/OT guidelines
• Case Study

Amyotrophic Lateral Sclerosis

• Degeneration of the motor neurons
• Genetic or generic disease?
  • Rule out everything else
• Risk factors and neuroprotection
• Medications help the complications
  • Alternative treatments
  • Stem cell research
• Palliative considerations

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